Different photo-thermal agents such as gold nanostructures with various shapes and sizes including nano-rods, nano-cages, nano-shells exhibit tunable optical properties, surface chemistry, resonance frequency and non-toxicity. Furthermore, gold nanoparticles (Au NPs) also utilized for diagnosis purposes and drug carriers for thermo-therapy of biological cells targets and potential bio-medical applications against various cancer treatments. To control complications of conventional cancer therapeutics, Stimuli-assisted drug delivery systems (DDS) together with interior and exterior Stimuli-assisted prompts have received particular interest by the scientific community around the globe. Among both of them, external stimuli-responsive parameters provide more controlled DDSs that circumvent individual discrepancy. Many researchers reported that light-responsive DDSs manifest interesting features because of proficiency and preferable spatiotemporal control. Among them, near-infrared light-responsive DDSs are potential candidates that follow various mechanisms such as photo-thermal effect, two photon absorption, and up converting nano-particles. This review presents an over view of different morphologies of Au nanostructures boosting the efficiency of DDSs by utilizing the phenomenon of surface plasmon resonance by overcoming the major challenges.

不同的光热剂（例如具有各种形状和大小的金纳米结构，包括纳米棒，纳米笼，纳米壳）具有可调的光学特性，表面化学性质，共振频率和无毒性。此外，金纳米颗粒（Au NPs）也用于诊断目的，并且将药物载体用于生物细胞靶标的热疗法以及针对各种癌症治疗的潜在生物医学应用。为了控制常规癌症治疗方法的并发症，刺激辅助药物输送系统（DDS）以及内部和外部刺激辅助提示已引起了全球科学界的特别关注。在这两者中，外部刺激响应参数提供了可控制的DDS，可以避免个体差异。许多研究人员报告说，由于熟练和较好的时空控制，对光敏感的DDS具有有趣的功能。其中，近红外光响应DDS是遵循各种机制（例如光热效应，两个光子吸收和上转换纳米粒子）的潜在候选物。这项审查提出了不同形态的金纳米结构，通过利用表面等离子体激元共振现象克服了主要挑战，从而提高了DDS的效率。