OBJECTIVES To investigate the prevalence of and factors associated with chronic insomnia and obstructive sleep apnea (CIOSA) comorbidity in obstructive sleep apnea (OSA) patients. METHODS Between March 2014 and March 2015, we conducted a prospective, cross-sectional study of 238 adults diagnosed with OSA according to polysomnography and International Classification of Sleep Disorders-Third Edition criteria. RESULTS The prevalence of CIOSA was 29%. There was a trend towards older age in the CIOSA group. Sex was not associated with CIOSA. Sleep-maintenance and sleep-onset insomnia predominated in the sample. Beck's depression and anxiety inventory scores were higher in the CIOSA group. Both depression and anxiety symptoms were associated with CIOSA. The arousal and apnea-hypopnea indices were lower in the CIOSA group. CIOSA was also associated with age ≥ 60 years and current tobacco use. Severe OSA and alcohol use were negatively associated with CIOSA. CONCLUSIONS Chronic insomnia is prevalent among OSA patients. Our study highlights the need for detailed evaluation of patients with sleep breathing disorders to diagnose other important sleep and mood disorders (such as depression and anxiety), given their frequent association.

中文翻译：

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阻塞性睡眠呼吸暂停患者慢性失眠的患病率

目的 调查阻塞性睡眠呼吸暂停 (OSA) 患者慢性失眠和阻塞性睡眠呼吸暂停 (CIOSA) 合并症的患病率和相关因素。方法 2014 年 3 月至 2015 年 3 月，我们对 238 名根据多导睡眠图和睡眠障碍国际分类第三版标准诊断为 OSA 的成年人进行了前瞻性横断面研究。结果 CIOSA 的流行率为 29%。CIOSA 组有老龄化趋势。性别与 CIOSA 无关。睡眠维持和睡眠发作失眠在样本中占主导地位。在 CIOSA 组中，Beck 的抑郁和焦虑量表得分更高。抑郁和焦虑症状都与 CIOSA 相关。CIOSA 组的觉醒和呼吸暂停低通气指数较低。CIOSA 还与年龄 ≥ 60 岁和当前烟草使用有关。严重的 OSA 和酒精使用与 CIOSA 呈负相关。结论 慢性失眠在 OSA 患者中很普遍。我们的研究强调需要对睡眠呼吸障碍患者进行详细评估，以诊断其他重要的睡眠和情绪障碍（例如抑郁和焦虑），因为它们经常发生关联。