When the year draws to a close, it is often symbolized by an old man who passes the mantle on to a newborn for the next year. With the passing of this mantle, we have completed another year of fantastic research, and it is time to celebrate the Top 10 original research articles for 2019–2020. These articles were chosen by the Immunology & Cell Biology (ICB) Editorial Team on 1 July 2020, from the manuscripts accepted in the previous 12 months and have been compiled here in our first Virtual Issue for 2021. Showcasing the high quality and breadth of immunological research published in ICB, these articles are revealed below in chronological order.

当这一年接近尾声时，它通常象征着一位老人将地幔传递给来年的新生儿。随着这个地幔的过去，我们又完成了一年的精彩研究，是时候庆祝 2019-2020 年 Top 10 原创研究文章了。这些文章由免疫学与细胞生物学( ICB ) 编辑团队于 2020 年 7 月 1 日从过去 12 个月接受的手稿中选出，并已在我们 2021 年的第一期虚拟期刊中汇编。发表在ICB 上的研究，这些文章按时间顺序显示如下。