Myotis nigricans is a species of bat from the Vespertilionidae family that is endemic of the Neotropical region. Its insectivorous feeding habit plus its large range of prey species, great geographical dispersion, wide colonies, and anthropomorphized behavior make this species an important ecological agent that acts in the control of nocturnal insects. Reproductively, M. nigricans presents geographic variations, having different patterns of reproduction according to its geographical location. Despite these extremely interesting characteristics, no more detailed study of the hormonal control of the reproduction of this species has been conducted. Therefore, the aim of the present study was to evaluate the variations in serum hormone concentrations and in uterine hormonal control of this bat during its different reproductive phases. Twenty adult females were collected, divided into four (4) sample groups, according to the reproductive status (nonreproductive, initial, and advanced pregnancy and lactating), and submitted to hormone dosage and immunohistochemical analyses. The results demonstrated that the uterus of M. nigricans is strongly regulated by the interaction/cross-talk between serum concentrations of estradiol (E2) and progesterone with their respective hormone receptors. Significant increases in the concentration of E2 and progesterone are needed to regulate the early pregnancy. The persistence of the corpus luteum throughout pregnancy is necessary, since its placenta does not express aromatase. The expressions of ERα and PR appear to be synchronized in order to coordinate a large portion of the processes that occur inside the uterus of M. nigricans during pregnancy and lactation.

中文翻译：

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蝙蝠黑鼠子宫在其不同生殖阶段的激素控制：强调黄体酮和雌二醇

Myotis nigricans 是一种来自新热带地区特有的蝙蝠科蝙蝠。其食虫性摄食习性加上其广泛的猎物种类、广泛的地理分布、广泛的群体和拟人化的行为，使该物种成为控制夜行性昆虫的重要生态因子。在繁殖方面，黑斑马齿苋表现出地域差异，根据其地理位置具有不同的繁殖模式。尽管有这些非常有趣的特征，但尚未对该物种繁殖的激素控制进行更详细的研究。因此，本研究的目的是评估该蝙蝠在不同生殖阶段的血清激素浓度和子宫激素控制的变化。收集了 20 名成年女性，根据生殖状态（非生殖、初始和晚期妊娠和哺乳期）分为四 (4) 个样本组，并进行激素剂量和免疫组织化学分析。结果表明，雌二醇 (E2) 和黄体酮的血清浓度与其各自的激素受体之间的相互作用/串扰强烈地调节了 M. nigricans 的子宫。需要显着增加 E2 和黄体酮的浓度来调节早期妊娠。黄体在整个怀孕期间的持续存在是必要的，因为它的胎盘不表达芳香化酶。ERα 和 PR 的表达似乎是同步的，以协调 M 子宫内发生的大部分过程。