Abstract

The aim was to determinate if the intermittent fasting enhances weight loss or muscle gains in humans younger than 60 years old. Multiple databases were searched up to May 2020 for studies in English, using MeSH terms and text words relating intermittent fasting, weight loss and muscle gains. The protocol was registered in PROSPERO. Study quality was assessed using NICE methodology. A total of 10 original articles were evaluated. Eight papers collected data through randomised controlled trials and two from cross-sectional study. Intermittent fasting could be beneficial in resistance trained subjects or in overweight individuals to improve body composition by decreasing fat mass and at least maintain muscle mass; decrease in GLP-1 levels and; improving health-related biomarkers such glucose and insulin levels. However, future studies are needed in order to better elucidate the effect of intermittent fasting on body composition.

摘要

目的是确定间歇性禁食是否会促进 60 岁以下人群的体重减轻或肌肉增加。截至 2020 年 5 月，使用 MeSH 术语和与间歇性禁食、体重减轻和肌肉增加相关的文本词搜索了多个数据库，以进行英语研究。该协议已在 PROSPERO 中注册。使用 NICE 方法评估研究质量。共评出10篇原创文章。八篇论文通过随机对照试验和两篇横断面研究收集了数据。间歇性禁食可能有益于抗阻力训练的受试者或超重的个体，通过减少脂肪量来改善身体成分，至少保持肌肉量；GLP-1 水平降低；改善与健康相关的生物标志物，例如葡萄糖和胰岛素水平。然而，