Laser-induced breakdown spectroscopy (LIBS) is a fast, low analytical cost, environmentally clean technique that does not require the use of reagents for sample preparation. However, regardless of the LIBS setup, it has limitations in terms of sensitivity and precision, especially when applied to complex samples, such as river sediment. To overcome these limitations, in this work, different experimental parameters were optimized for multi-element analysis of a river sediment sample using design of experiments (DOE) approaches, i.e., fractional factorial and central composite designs (CCD). The findings demonstrated that DOE applied to the LIBS technique can be used as an efficient tool for optimizing the key parameters affecting sediment analysis by LIBS.

激光诱导击穿光谱法（LIBS）是一种快速，分析成本低，环境清洁的技术，不需要使用试剂进行样品制备。但是，无论LIBS设置如何，它在灵敏度和精度方面都有局限性，尤其是在应用于复杂的样本（例如河底沉积物）时。为了克服这些限制，在这项工作中，使用实验设计（DOE）方法，即分数阶乘和中心复合设计（CCD），针对河流沉积物样品的多元素分析优化了不同的实验参数。研究结果表明，应用于LIBS技术的DOE可以用作优化影响LIBS沉积物分析的关键参数的有效工具。