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Topological recovery for non-rigid 2D/3D registration of coronary artery models
Computer Methods and Programs in Biomedicine ( IF 6.1 ) Pub Date : 2021-01-05 , DOI: 10.1016/j.cmpb.2020.105922
Siyeop Yoon , Chang Hwan Yoon , Deukhee Lee

Background and Objective: Intra-operative X-ray angiography, the current standard method for visualizing and diagnosing cardiovascular disease, is limited in its ability to provide essential 3D information. These limitations are disadvantages in treating patients. For example, it is a cause of lowering the success rate of interventional procedures. Here, we propose a novel 2D-3D non-rigid registration method to understand vascular geometry during percutaneous coronary intervention. Methods: The proposed method uses the local bijection pair distance as a cost function to minimize the effect of inconsistencies from center-line extraction. Moreover, novel cage-based 3D deformation and multi-threaded particle swarm optimization are utilized to implement real-time registration. We evaluated the proposed method for 154 examinations from 10 anonymous patients by coverage percentage, comparing the average distance of the 2D extracted center-line with that of the registered 3D center-line. Results: The proposed 2D-3D non-rigid registration method achieved an average distance of 1.98 mm with a 0.54 s computation time. Additionally, in aiming to reduce the uncertainty of XA images, we used the proposed method to retrospectively visualize the connections between 2D vascular segments and the distal part of occlusions. Conclusions: Ultimately, the proposed 2D/3D non-rigid registration method can successfully register the 3D center-line of coronary arteries with corresponding 2D XA images, and is computationally sufficient for online usage. Therefore, this method can improve the success rate of such procedures as a percutaneous coronary intervention and provide the information necessary to diagnose cardiovascular diseases better.



中文翻译:

冠状动脉模型的非刚性2D / 3D配准的拓扑恢复

背景与目的:术中X射线血管造影是目前可视化和诊断心血管疾病的标准方法,其提供基本3D信息的能力有限。这些局限性是治疗患者的不利条件。例如,这是降低介入手术成功率的原因。在这里,我们提出了一种新颖的2D-3D非刚性配准方法,以了解经皮冠状动脉介入治疗期间的血管几何形状。方法:所提出的方法使用局部双射对距离作为代价函数,以最大程度地减少中心线提取产生的不一致影响。此外,新颖的基于笼的3D变形和多线程粒子群优化技术可用于实现实时配准。我们比较了10个匿名患者的154种检查的提议方法(覆盖率),将2D提取的中心线与已注册的3D中心线的平均距离进行了比较。结果:所提出的2D-3D非刚性配准方法以0.54 s的计算时间实现了1.98 mm的平均距离。另外,为了减少XA图像的不确定性,我们使用所提出的方法回顾性地可视化2D血管段与闭塞远端之间的连接。结论:最终,所提出的2D / 3D非刚性配准方法可以成功地将冠状动脉的3D中心线与相应的2D XA图像配准,并且在计算上足以用于在线使用。因此,该方法可以提高诸如经皮冠状动脉介入治疗等手术的成功率,并提供更好地诊断心血管疾病所需的信息。

更新日期:2021-01-11
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