This minireview provides an overview on the current knowledge of protein–protein interactions, common characterisation methods to characterise them, and their role in protein complex formation with some examples. A deep understanding of protein–protein interactions and their molecular interactions is important for a number of applications, including drug design. Protein–protein interactions and their discovery are thus an interesting avenue for understanding how protein complexes, which make up the majority of proteins, work.

中文翻译：

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蛋白质相互作用的分子基础

这篇小型综述提供了有关蛋白质间相互作用的最新知识，表征它们的常用表征方法，以及它们在蛋白质复合物形成中的作用的概述。对蛋白质间相互作用及其分子相互作用的深刻理解对于包括药物设计在内的许多应用都很重要。因此，蛋白质与蛋白质的相互作用及其发现是了解构成大多数蛋白质的蛋白质复合物如何发挥作用的有趣途径。