ABSTRACT

Aim: To identify abnormalities in muscle tone and motor function associated with congenital Zika syndrome (CZS).

Method: A cross-sectional observational study involving 96 children (55 males) with CZS at a mean (SD) age 35.2 ± 2.9 months. Children’s muscle tone was investigated using the pull to sit, scarf sign, shoulder suspension and ventral suspension tests and the modified Ashworth scale (MAS). Motor impairment was determined using the Gross Motor Function Classification System (GMFCS) and body segments most affected with motor impairment.

Results: 58 (60,5%) children tested positive for ≥1 maneuver used to evaluate muscle tone, while 38 (39.5%) tested negative in all the tests. MAS score was >0 for at least one of the appendicular muscles in 91 children (94.8%). In 88 children (91.7%), all four limbs were affected.

Conclusion: Findings suggestive of axial hypotonia and appendicular hypertonia associated with severe motor impairment were prevalent in children with CZS.

摘要

目的：确定与先天性寨卡综合征 (CZS) 相关的肌肉张力和运动功能异常。

方法：一项横断面观察性研究，涉及 96 名平均 (SD) 年龄为 35.2 ± 2.9 个月的 CZS 儿童（55 名男性）。使用拉力坐姿、围巾征、肩悬和腹悬测试以及改良的 Ashworth 量表 (MAS)来研究儿童的肌肉张力。运动障碍是使用粗大运动功能分类系统 (GMFCS) 和受运动障碍影响最大的身体部位确定的。

结果：38时（39.5％）在所有的测试中呈阴性58（60.5％）的孩子测试呈阳性用于评估肌张力≥1演习。91 名儿童 (94.8%) 的至少一根附肢肌肉的 MAS 评分 >0。在 88 名儿童 (91.7%) 中，所有四肢都受到影响。

结论：在 CZS 儿童中普遍存在与严重运动障碍相关的轴性肌张力减退和四肢肌张力亢进的发现。