A convenient synthesis of 3-aroylisoxazoles from methyl ketones and (vinylsulfonyl)benzene in 2%TPGS-750-M/H₂O has been developed. This reaction proceeds via tandem tert-butyl nitrite-promoted Csp³-H functionalization of methyl ketones, 1,3-dipolar cycloaddition and base-catalyzed aromatization, providing the corresponding products in moderate to good yields.

中文翻译：

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由甲基芳基酮和水中的（乙烯基磺酰基）苯方便地合成4,5-未取代的3-芳基异恶唑

已经开发了在2％TPGS-750-M / H ₂ O中由甲基酮和（乙烯基磺酰基）苯方便地合成3-芳基异恶唑的方法。该反应通过亚甲基串联叔丁基亚硝酸盐促进的Csp ³ -H官能化，1，3-偶极环加成和碱催化的芳构化进行，从而以中等至良好的产率提供相应的产物。