Metal nanoparticles are widely applied in various biomedical applications because of their unique physicochemical properties. The new and unique properties of gold nanoparticles (AuNPs) including, biocompatibility, low cytotoxicity, and optical properties, make them valuable for applications of biomedical fields including, biosensing, bioimaging, cancer therapy of cancer, and drug delivery. Utilization of AuNPs in radiotherapy and photothermal therapy has created a novel platform for primary diagnosis and cancer therapy. Owing to AuNPs' large surface area, chemical functional groups or biological molecules like drug molecules can be immobilized on gold surface. Thus, the surface functionalization of AuNPs makes them a good carrier for targeted drug delivery. This review focuses on new progress in processes of the functionalization of AuNPs and their possible biomedical applications.

金属纳米颗粒由于其独特的物理化学性质而被广泛应用于各种生物医学应用中。金纳米粒子（AuNPs）的新奇独特特性包括生物相容性，低细胞毒性和光学特性，使其对于生物医学领域的应用有价值，包括生物传感，生物成像，癌症的癌症治疗和药物递送。AuNPs在放射治疗和光热疗法中的利用为初步诊断和癌症治疗创造了一个新的平台。由于AuNPs的表面积大，化学官能团或生物分子（如药物分子）可以固定在金表面。因此，AuNPs的表面功能化使其成为靶向药物递送的良好载体。