Choline chloride (ChCl) based natural deep eutectic solvents (NADES) were synthesized and tested as coagulant for stable bentonite colloidal suspensions. In this work, three ChCl based natural deep eutectic solvent NADES were synthesized by mixing choline chloride as the hydrogen bond acceptor (HBA) with lactic acid (LA), malic acid (MA), and citric acid (CA) as the hydrogen bond donors (HBD) with a molar ratio of 1:1. The analysis showed that there is no significant difference in the result, however, ChCl:LA was the easiest to synthesize and showed slightly higher efficiency at low dosage. For the determination of the optimum conditions, response surface methodology with central composite design was employed to generate an experimental design with two controlled variables: the ChCl:LA dosage and the bentonite solid content. The turbidity removal percentage, the reduction in zeta potential, the variation in the floc size of the sediments, and pH of the system were the design responses. However, due to the high turbidity removal percentage even at lower dosage of the coagulant and the constant removal percentage of almost 99 % led to excluding the turbidity as a response as it proves to be insignificant. By performing a multiple response optimization on the designed experiment, the optimum condition for the destabilization and separation process that results in a zeta potential of -5.8 mV, a pH of 2.2, D₅₀ of 31.5 μm and a D₉₀ 63.8 μm was found to be 77 mM and 3.48 g L⁻¹ for the ChCl:LA dosage and the bentonite solid content, respectively.

合成了基于氯化胆碱（ChCl）的天然深共熔溶剂（NADES），并测试了其作为稳定膨润土胶体悬浮液的凝结剂。在这项工作中，通过将作为氢键受体（HBA）的胆碱氯化物与作为氢键供体的乳酸（LA），苹果酸（MA）和柠檬酸（CA）混合，合成了三种基于ChCl的天然深共熔溶剂NADES。 （HBD）的摩尔比为1：1。分析表明，结果没有显着差异，但是，ChCl：LA的合成最容易，并且在低剂量下显示出更高的效率。为了确定最佳条件，采用了采用中心复合设计的响应面方法来生成具有两个控制变量的实验设计：ChCl：LA用量和膨润土固体含量。设计响应包括浊度去除百分比，ζ电势降低，沉积物絮凝物大小的变化以及系统的pH值。然而，由于即使在较低剂量的凝结剂下仍具有较高的浊度去除率，并且几乎99％的恒定去除率导致将浊度作为响应排除在外，因为事实证明这是微不足道的。通过对设计的实验进行多重响应优化，去稳定和分离过程的最佳条件将导致zeta电位为-5.8 mV，pH为2.2，D 由于即使在较低剂量的混凝剂下仍具有较高的浊度去除率，并且恒定去除率接近99％导致排除浊度作为响应，因为事实证明这是微不足道的。通过对设计的实验进行多重响应优化，去稳定和分离过程的最佳条件将导致zeta电位为-5.8 mV，pH为2.2，D 由于即使在较低剂量的混凝剂下仍具有较高的浊度去除率，并且恒定去除率接近99％导致排除浊度作为响应，因为事实证明这是微不足道的。通过对设计的实验进行多重响应优化，去稳定和分离过程的最佳条件将导致zeta电位为-5.8 mV，pH为2.2，D对于ChCl：LA剂量和膨润土固体含量，发现31.5μm中的₅₀和D ₉₀ 63.8μm分别为77 mM和3.48 g L ^-1。