Multiheteroatom-containing small-sized cyclic molecules such as 2- iminothiazolidines are often found to possess beneficial pharmacological properties. In this review article, the biological significance of 2-iminothiazolidines is discussed and the literature reports published in the last 15 years spanning from 2006 to 2020 describing various preparative routes to access 2-iminothiazolidine derivatives have been categorically and chronologically described. The notable synthetic methods discussed here involve ringexpansion transformations of nonactivated and activated aziridines, thiiranes, epoxides, and other miscellaneous reactions.

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2-亚氨基噻唑烷的合成途径：最先进的2006-2020年

经常发现含有多杂原子的小环状分子（例如2-亚氨基噻唑烷）具有有益的药理特性。在这篇综述文章中，对2-亚氨基噻唑烷类化合物的生物学意义进行了讨论，并分类和按时间顺序描述了从2006年至2020年的最近15年中发表的描述2-亚氨基噻唑烷衍生物的各种制备途径的文献报道。这里讨论的著名的合成方法涉及未活化和活化的氮丙啶，硫杂环丁烷，环氧化物和其他杂种反应的环扩环转化。