MIPs and surface enhanced Raman scattering (SERS) technology are combined to construct a new type of sensor for selective detection of chlorophenols. The SERS substrates are synthesized by loading Ag nanoparticles on MIL-101 (Fe). Then, the Ag@MIL-101 (Fe)@MIPs is obtained by precipitation polymerization with using 2,6-DCP as the template and acrylamide as the functional monomer. The synthesized MIL-101 (Fe) is found to be an octahedral structure. The prepared Ag@MIL-101 (Fe)@MIPs shows huge SERS activity. In the range of 10⁻³-10⁻⁹ mol/L, the prepared sensor for detecting 2,6-DCP has a linear relationship between SERS intensity at the peak of 1575 cm⁻¹ and 2,6-DCP concentration, the detection limit is 4.5 nmol/L, and the imprinting factor is 2.2. The sensor is used for actual sample analysis, with a recovery rate of 96.58%–105.56%, and a relative standard deviation (R²) of 1.355%–3.861%. The metal MOF-based nanocomposite prepared in this study can be used as a promising SERS substrate material. This method which is combined by MIPs and SERS provides a new detection method for the detection of 2,6-DCP and other chlorophenols, and expandes new technical fields.

MIP和表面增强拉曼散射（SERS）技术相结合，构成了一种用于选择性检测氯酚的新型传感器。通过将银纳米颗粒负载在MIL-101（Fe）上来合成SERS衬底。然后，以2，6-DCP为模板，丙烯酰胺为功能单体，通过沉淀聚合得到Ag @ MIL-101（Fe）@MIPs。发现合成的MIL-101（Fe）是八面体结构。制备的Ag @ MIL-101（Fe）@MIPs显示出巨大的SERS活性。在10 ^-3 -10 ^-9 mol / L的范围内，制备的用于检测2,6-DCP的传感器在峰值为1575 cm ^-1的SERS强度之间具有线性关系。和2,6-DCP浓度，检测限为4.5 nmol / L，印迹因子为2.2。该传感器用于实际样品分析，回收率为96.58％–105.56％，相对标准偏差（R ²）为1.355％–3.861％。在这项研究中制备的基于金属MOF的纳米复合材料可用作有希望的SERS衬底材料。该方法与MIP和SERS相结合，为检测2,6-DCP和其他氯酚提供了一种新的检测方法，并扩展了新的技术领域。