Purpose

To review the evidence on the usefulness of the multifocal visual evoked potential (mfVEP) test in patients with optic neuritis (ON) and/or multiple sclerosis (MS).

Methods

We critically review key published evidence on the use of mfVEP in ON/MS patients and its association with other functional and structural tests.

Results

Multifocal VEP tests are useful in detecting abnormality in patients with ON/MS and monitor the progression of lesions (remyelination, atrophy). In addition, mfVEP has good correlation with conventional visual evoked potential (VEP), standard automated perimetry, optical coherence tomography and magnetic resonance imaging. In patients with ON, mfVEP might be useful in predicting the risk of conversion to MS.

中文翻译：

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多焦视觉诱发电位在视神经炎和多发性硬化症患者中的作用：综述

目的

审查多焦视觉诱发电位 (mfVEP) 测试对视神经炎 (ON) 和/或多发性硬化症 (MS) 患者有用的证据。

方法

我们批判性地审查了关于在 ON/MS 患者中使用 mfVEP 及其与其他功能和结构测试关联的关键已发表证据。

结果

多焦点 VEP 测试可用于检测 ON/MS 患者的异常并监测病变的进展（髓鞘再生、萎缩）。此外，mfVEP 与常规视觉诱发电位 (VEP)、标准自动视野测量、光学相干断层扫描和磁共振成像具有良好的相关性。对于 ON 患者，mfVEP 可能有助于预测转化为 MS 的风险。