Background: Formation of the microbial colonies in the wet and damp environment affects the indoor air quality thus posing severe threats to human health. Health problems or Building- associated illness (any disease or infection) caused by being in a closed space or building are generally separated into two categories including building-related illness (BRI) and sick building syndrome (SBS). Considered by Pathognomy research, that biological pollutants or bioaerosols (bacteria, fungi and viruses like coronavirus), are the significant inducement for “sick building syndrome (SBS)” associated with a group of mucosal, skin, and general symptoms, characterized by tiredness; headaches; irritation of skin, nose, eyes, throat and mucous membranes, most prevalent in buildings like residential and occupational like offices, schools, hotels and hospitals.

背景：在潮湿环境中形成的微生物菌落会影响室内空气质量，从而对人类健康构成严重威胁。在封闭空间或建筑物中引起的健康问题或与建筑物有关的疾病（任何疾病或感染）通常分为两类，包括与建筑物有关的疾病（BRI）和建筑物不健康综合症（SBS）。病理学研究认为，生物污染物或生物气溶胶（细菌，真菌和冠状病毒等病毒）是与一组以疲倦为特征的粘膜，皮肤和一般症状相关的“病态建筑综合症（SBS）”的重要诱因；头痛 刺激皮肤，鼻子，眼睛，喉咙和粘膜，最常见于建筑物，例如住宅和职业，如办公室，学校，旅馆和医院。