A novel procedure for a one-pot cascade reaction of o-aminoacetophenones and aryl/aliphatic isocyanates catalyzed/oxidized by the [Pd]/[Ag] system was developed. The reaction involves two C–N bond and one C–C bond formations during the double annulation process and the desired indoloquinazolinones and derivatives were afforded up to 81% yields from readily available substrates with a tolerance of a broad variety.

中文翻译：

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邻氨基苯乙酮和异氰酸酯双环的快速方法制备吲哚并喹唑啉酮

提出了一种新的方法，用于[Pd] / [Ag]体系催化/氧化邻氨基苯乙酮与芳基/脂肪族异氰酸酯的一锅级联反应。该反应在双环化过程中涉及两个C–N键和一个C–C键的形成，所需的吲哚并喹唑啉酮及其衍生物可从现成的基质中获得高达81％的产率，且具有多种耐受性。