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The main DNA viruses significantly affecting pig livestock
Journal of Veterinary Research ( IF 1.8 ) Pub Date : 2020-12-29 , DOI: 10.2478/jvetres-2021-0001
Carlos Díaz 1 , Vladimír Celer 2 , Ivo Frébort 1
Affiliation  

Swine DNA viruses have developed unique mechanisms for evasion of the host immune system, infection and DNA replication, and finally, construction and release of new viral particles. This article reviews four classes of DNA viruses affecting swine: porcine circoviruses, African swine fever virus, porcine parvoviruses, and pseudorabies virus. Porcine circoviruses belonging to the Circoviridae family are small single-stranded DNA viruses causing different diseases in swine including poly-weaning multisystemic wasting syndrome, porcine dermatitis and nephropathy syndrome, and porcine respiratory disease complex. African swine fever virus, the only member of the Asfivirus genus in the Asfarviridae family, is a large double-stranded DNA virus and for its propensity to cause high mortality, it is currently considered the most dangerous virus in the pig industry. Porcine parvoviruses are small single-stranded DNA viruses belonging to the Parvoviridae family that cause reproductive failure in pregnant gilts. Pseudorabies virus, or suid herpesvirus 1, is a large double-stranded DNA virus belonging to the Herpesviridae family and Alphaherpesvirinae subfamily. Recent findings including general as well as genetic classification, virus structure, clinical syndromes and the host immune system responses and vaccine protection are described for all four swine DNA virus classes.

中文翻译:

主要的DNA病毒会严重影响猪的家畜

猪DNA病毒已经开发出独特的机制,可以逃避宿主免疫系统,感染和DNA复制,最后可以构建和释放新的病毒颗粒。本文介绍了影响猪的四类DNA病毒:猪圆环病毒,非洲猪瘟病毒,猪细小病毒和伪狂犬病病毒。属于圆环病毒科的猪圆环病毒是小的单链DNA病毒,可在猪中引起多种疾病,包括多断奶多系统消耗综合症,猪皮炎和肾病综合症以及猪呼吸道疾病综合症。非洲猪瘟病毒的唯一成员Asfivirus属中的非洲猪瘟病毒科家族,是一种大的双链DNA病毒,并且由于其具有导致高死亡率的倾向,目前被认为是养猪业中最危险的病毒。猪细小病毒是属于细小病毒科的小型单链DNA病毒,可引起孕妇小母猪的生殖衰竭。伪狂犬病病毒或猪疱疹疱疹病毒1是属于疱疹病毒科和阿尔法疱疹病毒亚科的大型双链DNA病毒。描述了所有四种猪DNA病毒类别的最新发现,包括一般以及遗传分类,病毒结构,临床综合症以及宿主免疫系统反应和疫苗保护。
更新日期:2020-12-29
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