Over the last decade, significant advancements have been made in the field of biosensing technology. With the rising demand for personalized healthcare and health management tools, electrochemical sensors are proving to be reliable solutions; specifically, impedimetric sensors are gaining considerable attention primarily due to their ability to perform label-free sensing. The novel approach of using Room Temperature Ionic Liquids (RTILs) to improve the sensitivity and stability of these detection systems makes long-term continuous sensing feasible towards a wide range of sensing applications, predominantly biosensing. Through this review, we aim to provide an update on current scientific progress in using impedimetric biosensing combined with RTILs for the development of sensitive biosensing platforms. This review also summarizes the latest trends in the field of biosensing and provides an update on the current challenges that remain unsolved.

在过去的十年中，生物传感技术领域取得了重大进步。随着对个性化医疗和健康管理工具需求的增长，电化学传感器被证明是可靠的解决方案。具体而言，阻抗传感器主要由于其执行无标签感测的能力而受到了广泛关注。使用室温离子液体（RTIL）来提高这些检测系统的灵敏度和稳定性的新颖方法使长期连续感测对于广泛的感测应用（主要是生物感测）可行。通过这次审查，我们旨在提供有关使用阻抗生物传感与RTIL结合开发敏感生物传感平台的最新科学进展的最新信息。