Knowing the “point of view” of the immune system is essential to understand the characteristic of a pandemic, such as that generated by the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)-2, responsible for the Coronavirus Disease (COVID)-19. In this review, we will discuss the general host/pathogen interactions dictating protective immune response or immunopathology, addressing the role of immunity or immunopathology in influencing the clinical infection outcome, and debate the potential immunoprophylactic and immunotherapy strategies required to fight the virus infection.

中文翻译：

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冠状病毒SARS-CoV-2的免疫系统图

了解免疫系统的“观点”对于了解大流行的特征至关重要，例如，这种大流行是由负责冠状病毒病（COVID）-19的严重急性呼吸系统综合症冠状病毒（SARS-CoV）-2产生的。在这篇综述中，我们将讨论指示保护性免疫应答或免疫病理学的一般宿主/病原体相互作用，探讨免疫或免疫病理学在影响临床感染结果中的作用，并讨论应对病毒感染所需的潜在免疫预防和免疫疗法策略。