The release of active pharmaceutical ingredients and their metabolites in surface waters and groundwater with insufficiently treated wastewaters nowadays may be a global environmental concern. In this study, simple, inexpensive, and solid phase procedure has been developed for the removal of pyridoxine hydrochloride (vitamin B₆, PDX) and ciprofloxacin (CPX) onto polyurethane foam (PUF) using the batch mode technique. PUF was characterized using scanning electron microscopy and FT-IR spectroscopy. The batch experiments indicated optimum conditions for the adsorption process at pH 5.6 for PDX and CPX. The optimum contact time to reach its best removal is 30 min for the removal of both drugs and the sorbent amount at 1.0 and 1.5 g for PDX and CPX, respectively. It was found that the experimental data for the adsorption of PDX fit well into Langmuir model with R² values (0.979). Whereas the adsorption of CPX follows Freundlich model with R² value (0.914). Adsorption process undergoes pseudo-first-order kinetic as proved by the high value of R² (0.973) and (0.956) for PDX and CPX, respectively. Experimental results have proven that PUF has a great potential for the removal of both drugs with maximum removal efficiency 50 and 98% for PDX and CPX, respectively.

中文翻译：

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在纯制剂和药物制剂中使用聚氨酯泡沫吸附去除维生素B6和环丙沙星的动力学和平衡研究

如今，未经充分处理的废水在地表水和地下水中释放活性药物成分及其代谢产物可能是全球环境关注的问题。在这项研究中，开发了一种简单，廉价且固相的方法来去除盐酸吡ido醇（维生素B ₆（PDX）和环丙沙星（CPX）使用分批模式技术注入聚氨酯泡沫（PUF）中。使用扫描电子显微镜和FT-IR光谱对PUF进行表征。批处理实验表明，PDX和CPX在pH 5.6的吸附过程的最佳条件。达到最佳去除效果的最佳接触时间是30分钟，以去除两种药物，PDX和CPX的吸附量分别为1.0 g和1.5 g。发现PDX吸附的实验数据非常适合R ²值（0.979）的Langmuir模型。而CPX的吸附遵循Freundlich模型，R ²值为（0.914）。R ²的高值证明吸附过程经历了拟一级动力学PDX和CPX分别为（0.973）和（0.956）。实验结果证明，PUF具有去除两种药物的巨大潜力，分别对PDX和CPX的最大去除效率分别为50％和98％。