The genus Millettia belongs to Fabaceae includes 200 species which are distributed in tropical and subtropical regions of the world. Plants belong to this genus are used as folkloric medicine, for the treatment of different ailments like in wound healing, boil, sores, skin diseases, snake bite, muscle aches, pains, rheumatic arthritis, and gynaecological diseases. The aim of the review is to provide updated, comprehensive and categorized information on the aspects of ethnobotanical, phytochemical, pharmacological uses and toxicity of genus Millettia in order to identify their therapeutic potential and generate space for future research opportunities. The present study comprises of isolated flavonoids, phenolic compounds, phytosterols, saponins, alkaloids, polysaccharides, terpenoids and resins and pharmacological activities of various Millettia species. The relevant data were searched by using the keyword “Millettia” in different scientific databases like, “Google Scholar”; “NISCAIR repository”; “Pub Med”; “Science Direct”; “Scopus” and the taxonomy is validated by “The Plant List”. This review discusses the existing information of the traditional evaluation as well as phytochemical and pharmacological evaluation of the extract and active constituents of the genus “Millettia”. This review confirms that several Millettia species have emerged as a high-quality medicine in a traditional system for arthritis, wound healing, inflammation, skin diseases. Numerous conventional uses of Millettia species have been validated by modern pharmacology research. Intensive investigations of the genus Millettia relating to phytochemistry and pharmacology, especially their mechanism of action, safety, and efficacy could be the future research interests by the researcher in the area of phytomedicine.

Millettia属Fabaceae，包括200种，分布在世界热带和亚热带地区。属于该属的植物被用作民俗医学，用于治疗各种疾病，例如伤口愈合，疮，疮，皮肤病，蛇咬伤，肌肉疼痛，疼痛，风湿性关节炎和妇科疾病。审查的目的是提供关于Millettea属植物植物学，植物化学，药理学用途和毒性方面的最新，全面和分类信息，以便确定其治疗潜力并为未来的研究机会创造空间。本研究包括分离的类黄酮，酚类化合物，植物甾醇，皂苷，生物碱，多糖，千足莲属植物的萜类化合物和树脂以及药理活性。通过在不同的科学数据库（例如“ Google Scholar”）中使用关键字“ Millettia”来搜索相关数据；“ NISCAIR资料库”；“ Pub Med”；“直接科学”；“ Scopus”和分类法已通过“ The Plant List”进行了验证。这篇综述讨论了“ Millettia”属提取物和活性成分的传统评价以及植物化学和药理学评价的现有信息。这项审查证实，在传统的关节炎，伤口愈合，炎症，皮肤疾病的系统中，数种千足莲已经成为一种优质药物。现代药理研究证实了千足莲属植物的许多常规用途。