Saudi Pharmaceutical Journal ( IF 4.1 ) Pub Date : 2020-12-29 , DOI: 10.1016/j.jsps.2020.12.012 Mandlin Abdulaziz Almousa 1, 2 , Ghadah Khalid Alharbi 1, 2 , Amerah Saeed Alqahtani 1, 2 , Yusra Chachar 2, 3 , Lubna Alkadi 2, 3, 4 , Ali Aboalela 2, 3, 4
Background
Medication-related osteonecrosis of the jaw (MRONJ) is a complication affecting patients who are being treated with antiresorptive or antiangiogenic medication. These patients require meticulous treatment planning and management strategies. This research aimed to assess the knowledge of dental practitioners and students in their professional years regarding MRONJ.
Methods
A cross-sectional study was conducted among 345 dental practitioners and students in their professional years of both genders, in governmental and private dental schools. The data was collected using an electronic and paper-based self-administered structured questionnaire with six sections. The data was entered and analyzed using SPSS Version 23, and a P-value <0.05 was considered significant. A Chi-square test was used to compare the categorical variables.
Results
Though more than half of the sample 68% received information about antiresorptive and antiangiogenic drugs during their studies, the level of knowledge was low. The primary diseases targeted by antiresorptive and antiangiogenic medications were not known by the majority of the sample. Almost half of the sample could not identify any antiresorptive or antiangiogenic medication and only 28.1% knew the correct definition of MRONJ.
Conclusion
The level of knowledge regarding MRONJ is a concern, necessitating more educational courses and workshops.
中文翻译:
牙科医生和学生对药物相关颌骨坏死(MRONJ)的认识
背景
药物相关的颌骨坏死 (MRONJ) 是一种影响正在接受抗再吸收或抗血管生成药物治疗的患者的并发症。这些患者需要细致的治疗计划和管理策略。本研究旨在评估牙科医生和学生在其职业生涯中关于 MRONJ 的知识。
方法
一项横断面研究在政府和私立牙科学校的 345 名牙科医生和学生中进行,他们的职业年龄不限,男女不限。使用包含六个部分的电子和纸质自我管理结构化问卷收集数据。使用SPSS 23版输入和分析数据,P值<0.05被认为是显着的。卡方检验用于比较分类变量。
结果
尽管超过一半的样本 68% 在研究期间收到了有关抗再吸收和抗血管生成药物的信息,但知识水平很低。大多数样本不知道抗吸收和抗血管生成药物针对的主要疾病。几乎一半的样本无法识别任何抗再吸收或抗血管生成药物,只有 28.1% 知道 MRONJ 的正确定义。
结论
关于 MRONJ 的知识水平是一个问题,需要更多的教育课程和研讨会。