Xq25 microduplication syndrome is a recognized syndrome presenting intellectual disability and distinctive facial appearance. We generated an induced pluripotent stem cell (iPSC) line from peripheral blood mononuclear cells (PBMCs) of an 8-year-old boy with Xq25 Microduplication Syndrome carrying a 1.3 Mb hemizygote duplication at chrXq25. The iPSCs expressed pluripotency markers, free of genomically integrated episomal plasmids, with normal karyotype and three layers’ differentiation potential in vitro.

中文翻译：

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Xhr25微复制综合征患者在chrXq25处携带1.3 Mb半合子复制的非整合iPS细胞系（SDQLCHi023-A）的建立

Xq25微复制综合征是一种公认​​的综合征，具有智力残疾和独特的面部外观。我们从一个8岁的Xq25微复制综合征的男孩的外周血单核细胞（PBMC）生成了诱导多能干细胞（iPSC）系，该综合征在chrXq25携带1.3 Mb的半合子复制。iPSCs表达多能性标记，不含基因组整合的附加型质粒，在体外具有正常的核型和三层分化潜能。