Transition-metal-catalyzed direct C¨CH/C¨CH cross-coupling reactions as efficient and atom-economical approaches have been widely used to build up complex heterocyclic compounds. However, the strategy for preparation of biphenyl-2-carbonitriles has not been well established. Herein, we described the first cyanogen directed Rh(III)- catalyzed CDC reaction of aromatic nitriles with heteroarenes. Various biphenyl-2-carbonitrilederivatives were obtained with broad functional group compatibility.

中文翻译：

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Rh（III）催化的芳族腈与杂芳烃的直接交叉脱氢偶联：快速获得双杂芳基-2-腈

过渡金属催化的直接C / CH交叉偶联反应作为一种有效且原子经济的方法已被广泛用于构建复杂的杂环化合物。然而，联苯-2-腈的制备策略尚未得到很好的确立。在这里，我们描述了芳香族腈与杂芳烃的第一个氰基直接的Rh（III）催化的CDC反应。获得了具有宽泛的官能团相容性的各种联苯-2-碳腈基衍生物。