This study compared the effects of adding acceptance and commitment therapy (ACT) or exposure and response prevention (ERP) to adults diagnosed with obsessive compulsive disorder (OCD) already on an optimal and stable dose of selective serotonin reuptake inhibitors (SSRIs). Forty adults on SSRIs who were diagnosed with OCD participated in a randomized controlled trial in Iran of 12 individual weekly sessions of either ACT+SSRI, ERP+SSRI, or continued SSRI only. The results showed significant reductions in OCD symptom severity in ACT+SSRI and ERP+SSRI conditions at posttreatment with significantly greater reductions in both conditions compared to SSRI-only at follow-up. Additionally, psychological inflexibility and use of thought control strategies significantly decreased in the ACT+SSRI condition at posttreatment and follow-up compared to the ERP+SSRI and SSRI conditions. Both conditions led to decreases in perceived importance of stop signals. Results provide cross-cultural support for the treatment of OCD using ACT and ERP as adjuncts to SSRI and modest process of change differences between ACT and ERP. Future directions and study limitations are discussed.

本研究比较了在已诊断为患有强迫症 (OCD) 的成人中添加接受和承诺治疗 (ACT) 或暴露和反应预防 (ERP) 对已使用最佳和稳定剂量的选择性血清素再摄取抑制剂 (SSRI) 的影响。四十名被诊断患有强迫症的 SSRI 成年人参加了在伊朗进行的一项随机对照试验，该试验每周进行 12 次单独的 ACT+SSRI、ERP+SSRI 或仅继续 SSRI 的会议。结果显示，治疗后 ACT+SSRI 和 ERP+SSRI 条件下的强迫症症状严重程度显着降低，与随访时仅 SSRI 相比，这两种条件下的下降幅度显着更大。此外，与 ERP+SSRI 和 SSRI 条件相比，ACT+SSRI 条件在治疗后和随访期间的心理不灵活和思维控制策略的使用显着降低。这两种情况都导致停止信号的感知重要性降低。结果为使用 ACT 和 ERP 作为 SSRI 的辅助手段治疗强迫症提供了跨文化支持，以及 ACT 和 ERP 之间的适度变化过程差异。讨论了未来的方向和研究限制。