The effects of social isolation on an individual's behavior is an important field of research, especially as public health officials encourage social distancing to prevent the spread of pandemic disease. In this study we evaluate the effects of social isolation on physical activity in mice. Utilizing a pixel‐based tracking system, we continuously monitored the movement of isolated mice compared with paired cage mates in the home cage environment. We demonstrate that mice that are socially isolated dramatically decrease their movement when separated from their cage mate, and especially in the dark cycle, when mice are normally most active. When isolated mice are re‐paired with their original cage mate, this effect is reversed, and mice return to their prior levels of activity. These findings suggest a close link between social isolation and physical activity, and are of particular interest in the wake of coronavirus disease 2019, when many are forced into isolation. Social isolation may affect an individual's overall activity levels in humans too, which may have unintended effects on health that deserve further consideration.

中文翻译：

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社会隔离与雄性小鼠体育活动的显着减少密切相关

社会隔离对个人行为的影响是一个重要的研究领域，尤其是当公共卫生官员鼓励社会疏远以防止大流行性疾病传播时。在这项研究中，我们评估了社交隔离对小鼠身体活动的影响。利用基于像素的跟踪系统，我们连续监控了孤立的小鼠的运动情况，并与家庭笼环境中的成对笼伴侣进行了比较。我们证明了与社会隔离的小鼠与笼伴侣分离时会大大降低其运动，尤其是在黑暗周期中，这通常是小鼠最活跃的时候。当隔离的小鼠与原始的笼伴侣重新配对时，这种作用被逆转，小鼠恢复到以前的活动水平。这些发现表明社会隔离与体育活动之间存在密切联系，特别是在2019年冠状病毒疾病之后，许多人被迫隔离，这引起了人们的特别关注。社会隔离也可能影响个人在人类中的整体活动水平，这可能对健康产生意想不到的影响，值得进一步考虑。