Induced pluripotent stem cells (iPSCs) have differentiation potential into different somatic cell types in vitro and are a useful tool to investigate pathomechanistic and cellular processes. In this study, we generated human induced pluripotent stem cells (iPSC) ZZUNEUi012-A from an apparently healthy female individual using an integration-free reprogramming method. The generated hiPSC line was pluripotent and had normal karyotype, showed robust expression of pluripotency markers and could differentiate into all three germ layers in vitro.

中文翻译：

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由健康女性个体产生hiPSC系ZZUNEUi012-A

诱导的多能干细胞（iPSC）在体外具有分化为不同体细胞类型的潜力，并且是研究病理机制和细胞过程的有用工具。在这项研究中，我们使用无积分重编程方法从表面健康的女性个体中产生了人诱导的多能干细胞（iPSC）ZZUNEUi012-A。产生的hiPSC品系是多能的，具有正常的核型，显示了多能性标记物的稳定表达，并且可以在体外分化为所有三个胚层。