The design, fabrication, and application of edible nanoemulsions for the encapsulation and delivery of bioactive agents has been a highly active research field over the past decade or so. In particular, they have been widely used for the encapsulation and delivery of hydrophobic bioactive substances, such as hydrophobic drugs, lipids, vitamins, and phytochemicals. A great deal of progress has been made in creating stable edible nanoemulsions that can increase the stability and efficacy of these bioactive agents. This article highlights some of the most important recent advances within this area, including increasing the water-dispersibility of bioactives, protecting bioactives from chemical degradation during storage, increasing the bioavailability of bioactives after ingestion, and targeting the release of bioactives within the gastrointestinal tract. Moreover, it highlights progress that is being made in creating plant-based edible nanoemulsions. Finally, the potential toxicity of edible nanoemulsions is considered.

在过去十年左右的时间里，用于封装和递送生物活性剂的可食用纳米乳液的设计、制造和应用一直是一个非常活跃的研究领域。特别是，它们已广泛用于疏水性生物活性物质的封装和递送，例如疏水性药物、脂质、维生素和植物化学物质。在创造稳定的可食用纳米乳液方面取得了很大进展，可以提高这些生物活性剂的稳定性和功效。本文重点介绍了该领域的一些最重要的最新进展，包括提高生物活性物质的水分散性、保护生物活性物质在储存过程中免受化学降解、提高生物活性物质摄入后的生物利用度、并针对胃肠道内生物活性物质的释放。此外，它强调了在创造植物性可食用纳米乳液方面取得的进展。最后，考虑了可食用纳米乳液的潜在毒性。