Recently, a straightforward one-pot method for ¹⁸F-fluoroethylation without azeotropic drying of cyclotron-produced [¹⁸F]F⁻ was developed. In this study, we have attempted to simplify the automated radiosynthesis of two [¹⁸F]fluoroethylated tracers, [¹⁸F]FEDAC and [¹⁸F]FET, using a desmethyl labeling precursor and [¹⁸F]fluoroethyl tosylate, based on the above-mentioned method. The radiochemical yields of [¹⁸F]FEDAC and [¹⁸F]FET were 26 ± 3.7% (n = 5) and 14 ± 2.2% (n = 4), respectively, based on total [¹⁸F]F⁻ at the end of irradiation.

中文翻译：

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通过使用[ ¹⁸ F]氟乙基甲苯磺酸盐的简化的一锅式¹⁸ F-氟乙基化方法放射性合成¹⁸ F-氟乙基化示踪剂

近来，对于一个简单的单釜法¹⁸无的回旋加速器产生的[共沸干燥F-fluoroethylation ¹⁸ F]˚F ^-开发的。在上述研究中，基于上述研究，我们尝试使用去甲基标记前体和[ ¹⁸ F]氟乙基甲苯磺酸酯简化两个[ ¹⁸ F]氟乙基化示踪剂[ ¹⁸ F] FEDAC和[ ¹⁸ F] FET的自动放射合成。提到的方法。 基于总的[ ¹⁸ F] F ^-，[ ¹⁸ F] FEDAC和[ ¹⁸ F] FET的放射化学产率分别为26±3.7％（n  = 5）和14±2.2％（n = 4）^- 在辐照结束时。