The objective of this study was to develop an innovative and advanced integrated “membrane and oxidation” system for the treatment of domestic wastewater by coupling membrane bioreactor (MBR), nanofiltration (NF) and ozonation. Five contaminants were selected (acetaminophen, carbamazepin, sulfamethoxazole, tetracyclin and terbutryn). The MBR effluent samples have been fully characterized using conventional analysis (COD, TOC, UV254, ionic chromatography…) and advanced characterization analyses (3D fluorescence excitation–emission matrices (3DEEM)) before being spiked with 1 ppm of each of the selected pharmaceuticals. NF process experiments were carried out in batch and semi-batch mode using a flat sheet membrane system (NF-90). Selected OMPs were well rejected by NF (between 84 % and 98 %) and the main fouling mechanisms observed were pore blocking and gel layer formation. MBR effluent was then pre-treated in an ozonation pilot unit’s with ozone gas inlet fixed at 5 g.Nm⁻³.The complete degradation by ozonation of carbamazepine and sulfamethoxazole took 15–20 min and more than 30 min for terbutryn. Acetaminophen, tetracyclin and dissolved organic matter were almost totally ozonated in 5 min. The overall mineralization rate was low. The pre-ozonation enables the NF fouling resistance to be decreased by almost 40 %.

这项研究的目的是通过结合膜生物反应器（MBR），纳滤（NF）和臭氧化技术，开发一种创新和先进的集成“膜和氧化”系统来处理生活污水。选择了五种污染物（对乙酰氨基酚，卡马西平，磺胺甲恶唑，四环素和特布特丁）。使用常规分析（COD，TOC，UV254，离子色谱法...）和高级表征分析（3D荧光激发-发射矩阵（3DEEM））对MBR废水样品进行了全面表征，然后对每种选定的药物加标1 ppm。使用平板膜系统（NF-90）以分批和半分批模式进行NF工艺实验。选定的OMP被NF很好地排斥（介于84％和98％之间），观察到的主要污垢机理是孔堵塞和凝胶层形成。然后将MBR废水在臭氧化试验装置中进行预处理，并将臭氧气体入口固定在5 g.Nm⁻³。卡马西平和磺胺甲恶唑的臭氧完全降解反应需要15–20分钟，而特布替林则需要30分钟以上。对乙酰氨基酚，四环素和溶解的有机物在5分钟内几乎全部被臭氧化。总体矿化率低。预臭氧处理可使NF结垢阻力降低近40％。