Abstract

For the first time it is shown that the development of resistance to melittin in Acholeplasma laidlawii, a mycoplasma that is widely spread in nature and that is the main contaminant of cell cultures and vaccines, is associated with significant changes in the genomic profile, in cellular and vesicular proteomes, as well as in virulence.

中文翻译：

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支原体对抗菌肽的适应性：羊膜鞘中蜂毒毒素抗性的发展与基因组和蛋白质组学特征以及毒力的变化有关

摘要

首次表明，在自然界中广泛传播并且是细胞培养物和疫苗的主要污染物的支原体-无花小球菌中，对蜂毒蛋白的抗性发展与细胞中基因组谱的显着变化有关。和水泡蛋白质组以及毒力。