We implemented HPTN 062, an acceptability and feasibility study of a motivational-interviewing (MI) intervention to reduce HIV transmission among individuals with acute HIV infection (AHI) in Lilongwe, Malawi. Participants were randomly assigned to receive either brief education or the MI intervention over 24 weeks; all participants received the same messages about AHI. We used mixed methods to assess participants' understanding of the association between AHI and viral load, and its connection to sexual behavior at 8 weeks. While most participants understood key aspects of AHI, MI-intervention participants gave substantially more detailed descriptions of their understanding. Nearly all participants, regardless of study arm, understood that they were highly infectious and would be very likely to transmit HIV after unprotected sex during AHI. Our findings suggest that messages about AHI delivered during the period of AHI are likely beneficial for ensuring that those with AHI understand their level of infectiousness and its association with forward transmission.

中文翻译：

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对马拉维利隆圭的急性HIV感染者感知的传染性及其对性行为的影响（HPTN 062）

我们实施了HPTN 062，这是一项动机访谈（MI）干预措施的可接受性和可行性研究，旨在减少马拉维利隆圭的急性HIV感染（AHI）患者之间的HIV传播。参与者被随机分配在24周内接受简短教育或MI干预；所有参与者都收到了有关AHI的相同消息。我们使用混合方法评估参与者对AHI和病毒载量之间的关联以及在8周时与性行为的联系的理解。虽然大多数参与者了解AHI的关键方面，但MI干预参与者对他们的理解进行了更为详细的描述。几乎所有参与者，无论研究机构如何，都知道他们具有高度传染性，并且在AHI期间未经保护的性行为之后很可能会传播HIV。