Medical male circumcision is a proven method of HIV risk reduction in men with no known direct benefit to women. We investigated the benefit of partner circumcision on women's health. We conducted a secondary analysis of 5,029 women enrolled in the Vaginal and Oral Interventions to Control the Epidemic trial across 15 African sites, to look at the impact of partner circumcision status on sexually transmitted infections, pregnancy, frequency of sex, and condom use in women. Of 4,982 participants with a baseline response, 31% had circumcised partners. Women with circumcised partners had a significantly reduced risk of syphilis acquisition, hazard ratio 0.51 (0.26, 1.00), p value = .05. Participants with uncircumcised partners were significantly less likely to have used a condom at the last sex act than the other two groups, adj. relative risk 0.86 (0.80, 0.92), adj. p value < .0001. We found no evidence of sexual risk compensation in women with circumcised partners.

中文翻译：

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男性伴侣包皮环切术对女性健康结局的影响

男性割礼是一种行之有效的降低男性HIV风险的方法，对女性没有直接的好处。我们调查了伴侣包皮环切术对女性健康的益处。我们对在15个非洲站点进行的阴道和口腔干预以控制流行病试验的5,029名妇女进行了二次分析，以研究伴侣包皮环切状态对女性性传播感染，怀孕，性行为频率和使用避孕套的影响。在有基线反应的4,982名参与者中，有31％有割礼的伴侣。有割礼伴侣的女性患梅毒的风险显着降低，危险比0.51（0.26，1.00），p值= 0.05。与未割包皮伴侣的参与者在最后一次性行为中使用安全套的可能性明显低于其他两组。相对风险0。86（0.80，0.92），可调 p值<.0001。我们没有发现有割礼伴侣的女性发生性风险补偿的证据。