An embodied conversational agent can serve as a relational agent and provide information, motivation, and behavioral skills. To evaluate the feasibility, acceptability, and preliminary efficacy of My Personal Health Guide, a theory-based mobile-delivered embodied conversational agent intervention to improve adherence to antiretroviral therapy in young African American men who have sex with men, we conducted this prospective pilot study using a 3-month pre-post design. Outcome measures included adherence, acceptability, feasibility, pre versus post health literacy, and pre versus post self-efficacy. There were 43 participants. Pill count adherence > 80% improved from 62% at baseline to 88% at follow-up (p = .05). The acceptability of the app was high. Feasibility issues identified included loss of usage data from unplanned participant app deletion. Health literacy improved whereas self-efficacy was high at baseline and follow-up. This pilot study of My Personal Health Guide demonstrated acceptability and preliminary efficacy in improving adherence in this important population.

中文翻译：

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基于理论的关系体现的会话代理移动电话干预在年轻的HIV阳性的非裔美国MSM中促进HIV药物依从性的可接受性，可行性和初步功效

体现的对话代理可以充当关系代理，并提供信息，动机和行为技能。为了评估《我的个人健康指南》的可行性，可接受性和初步疗效，这是一项基于理论的移动提供的体现性对话剂干预措施，旨在改善与男性发生性关系的年轻非洲裔美国男性对抗逆转录病毒疗法的依从性，我们进行了这项前瞻性研究使用3个月的后期设计。结果指标包括依从性，可接受性，可行性，健康素养前后的对比以及自我效能感对比后的对比。有43位参与者。服药> 80​​％的患者从基线时的62％改善到随访时的88％（p = .05）。该应用程序的接受度很高。确定的可行性问题包括因计划外的参与者应用删除而导致使用数据丢失。在基线和随访中，健康素养得到改善，而自我效能感却很高。我的《个人健康指南》的这项初步研究证明了在这一重要人群中改善依从性的可接受性和初步疗效。