A rapid, sensitive, environmental friendly dual preconcentration method by combining micro matrix solid‐phase dispersion extraction with field‐enhanced sample injection and micelle to cyclodextrin stacking has been developed for the determination of furocoumarins. Molecular sieve, KIT‐6, was used as an adsorbent in micro matrix solid‐phase dispersion process. The important parameters affecting off‐line and online CE preconcentration efficiency were optimized. Under the optimal experimental conditions, all analytes showed good linearity (R² > 0.999). The LODs of notopterol, isoimperatorin, and imperatorin were 0.1 μg/mL, 1.2 mg/kg, and 1.0 mg/kg, respectively. Compared with the normal CE method, the enrichment times were up to 300. Moreover, Angelicae Dahuricae Radix was used as the mode of complex solid sample matrix to demonstrate the prospect of application of this methodology. The results showed the proposed strategy is promising for determining trace furocoumarins in complex matrix samples, which might be applied as a powerful and economic tool in monitoring illegal cosmetic adding.

中文翻译：

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微基质固相分散萃取与现场增强进样和胶束到环糊精堆叠相结合的双预浓缩方法用于中性香豆素的灵敏分析

开发了一种快速、灵敏、环保的双重预浓缩方法，该方法将微基质固相分散萃取与场增强进样和胶束到环糊精堆积相结合，用于测定呋喃香豆素。分子筛 KIT-6 在微基质固相分散过程中用作吸附剂。优化了影响离线和在线CE预浓缩效率的重要参数。在最佳实验条件下，所有分析物均表现出良好的线性（R ²> 0.999)。诺托特罗、异欧前胡素和欧前胡素的 LOD 分别为 0.1 μg/mL、1.2 mg/kg 和 1.0 mg/kg。与普通CE方法相比，富集倍数可达300倍。此外，以白芷作为复杂固体样品基质的模式，展示了该方法的应用前景。结果表明，所提出的策略有望用于测定复杂基质样品中的痕量呋喃香豆素，可作为一种强大且经济的工具用于监测非法化妆品添加。