Abstract

Radiobiological experiments with the irradiation of various biological samples by nuclei from boron to neon with a primary energy of 30–50 MeV/nucleon are performed on the U400M cyclotron of the Laboratory of Nuclear Reactions, Joint Institute for Nuclear Research. The linear energy transfer (LET) of the nuclei in samples is calculated using the code Lise++. For reducing the energy of nuclei and increasing their LET, aluminum filters with different thickness are placed before samples. The presence of filters and other absorbers before a sample results in the production of secondary charged particles whose LET may strongly differ from the LET of primary nuclei of the beam. This also affects the accuracy of calculating the absorbed dose. For this reason, detailed calculations of particle fields in samples are performed using the Monte Carlo code for radiation transport in matter PHITS 3.20 for several variants of sample irradiation with thick absorbers before samples. The calculated LET distributions are analyzed and compared with the calculations using the code Lise++.

中文翻译：

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在U400M回旋加速器的放射生物学实验中计算线性能量转移分布

摘要

在联合核研究所联合实验室核反应实验室的U400M回旋加速器上，以30-50 MeV /核子的一次能，用原子核从硼到氖辐照了各种生物样品，进行了放射生物学实验。使用代码Lise ++计算样品中核的线性能量转移（LET）。为了减少原子核的能量并增加其LET，在样品之前放置了具有不同厚度的铝过滤器。样品之前存在过滤器和其他吸收剂会导致产生次级带电粒子，其LET可能与电子束主核的LET强烈不同。这也会影响计算吸收剂量的准确性。为此原因，使用蒙特卡洛代码对物质PHITS 3.20中的辐射传输进行了样品中粒子场的详细计算，用于在样品之前用厚吸收剂辐照样品的几种方法。使用代码Lise ++对计算出的LET分布进行分析，并与计算结果进行比较。