The purpose of this study is to evaluate the effectiveness of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders adapted for homeless women (UPHW). Eighty-one homeless women participated in this single-blinded quasi-experimental clinical trial, involving up to 12 sessions of group treatment, and 3-and 6-month follow-ups. The participants received either immediate treatment with the UPHW (n = 46) or delayed treatment, following a 12-week wait-list control period (WLC; n = 35). Primary outcomes included depression and anxiety. Secondary measures comprised positive and negative affect, psychological well-being, health perception, and social support. The UPHW resulted in significant improvement on measures of anxiety, depression and negative affect. Improvements in anxiety and depression were maintained over a 3-month follow-up period, but not at 6-month. The reliability of the clinical changes showed significant differences between UPHW and WLC for depression. Moreover, the inter-session assessment in the UPHW group showed a linear trend reduction for depression and anxiety scores along the 12 sessions. The clinical implications on the UPHW in social settings are also discussed.

本研究的目的是评估适用于无家可归妇女的情绪障碍跨诊断治疗统一协议 (UPHW) 的有效性。81 名无家可归的妇女参加了这项单盲准实验性临床试验，涉及多达 12 次集体治疗，以及 3 个月和 6 个月的随访。在 12 周的等待名单控制期 (WLC ; n = 35)。主要结果包括抑郁和焦虑。次要指标包括正面和负面影响、心理健康、健康感知和社会支持。UPHW 显着改善了焦虑、抑郁和负面影响的指标。焦虑和抑郁的改善在 3 个月的随访期内得到维持，但在 6 个月时没有。临床变化的可靠性显示 UPHW 和 WLC 对抑郁症的显着差异。此外，UPHW 组的会话间评估显示，在 12 个会话期间，抑郁和焦虑评分呈线性下降趋势。还讨论了 UPHW 在社会环境中的临床意义。