Cosmeceutical field, which merges cosmetics and pharmaceuticals , is nowadays a highly investigated research area, because a scientific demonstration of the claimed bioactivity of new cosmeceutical ingredients is increasingly requested. In fact, an aspect differentiating traditional cosmetics from cosmeceuticals is the identification and characterization of the active ingredients and demonstrating its efficacy in the claimed activity. An interesting group of bioactive cosmeceutical ingredients are peptides, which meets most of the requirements presented by the cosmeceutical industry when composing new formulas. In this context, beside bioactivity, two additional aspects have been recently considered, when dealing with peptides as cosmeceutical ingredients: bioavailability and stability. We describe herein novel methods applied in order to enhance peptides skin-penetration and stability, reviewing both scientific papers and patents, issued in the cosmeceutical arena.

中文翻译：

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肽作为活性成分：药妆行业的挑战

合并化妆品和药品的药妆领域如今是一个高度研究的研究领域，因为越来越需要对新药妆成分所声称的生物活性进行科学论证。事实上，将传统化妆品与药妆品区分开来的一个方面是活性成分的鉴定和表征，并证明其在要求保护的活性中的功效。一组有趣的生物活性药妆成分是肽，它满足药妆行业在配制新配方时提出的大部分要求。在这种情况下，除了生物活性外，最近在将肽作为药妆成分处理时还考虑了另外两个方面：生物利用度和稳定性。