Natural Product Communications ( IF 1.8 ) Pub Date : 2020-12-21 , DOI: 10.1177/1934578x20982111 Yunqi Yang 1 , Linlin Wang 1 , Man Yuan 1 , Qi Yu 1 , Fenghua Fu 1
Escin is a triterpenoid saponin extracted from the fruit of Aesculus wilsonii Rehd. and Aesculus hippocastanum (Hippocastanaceae). Clinically, it is widely used in the treatment of edema induced by either trauma or surgery, as well as treating chronic venous insufficiency. The anti-inflammatory and antiedema effects of escin have been extensively investigated. This article systematically reviews the effects of escin on inflammation and gastrointestinal diseases, including its role in inflammation, as an antioxidant, and in inhibiting gastric acid secretion and promoting gastrointestinal movement, especially, the molecular mechanism. The advantages and potential uses of escin have also been discussed.
中文翻译:
Escin的抗炎和胃肠保护作用
Escin是一种三萜皂苷,是从欧洲七叶树果实中提取的。和七叶树河马(河马科)。在临床上,它被广泛用于治疗由外伤或手术引起的水肿,以及治疗慢性静脉功能不全。七叶红素的抗炎和抗水肿作用已被广泛研究。本文系统地综述了七叶红素对炎症和胃肠道疾病的影响,包括其在炎症中的作用(作为抗氧化剂)以及抑制胃酸分泌和促进胃肠道运动,特别是分子机制。七叶红素的优点和潜在用途也已经讨论过。