Conventional chemical approaches for synthesizing nanoparticles (NPs) may restrict their applicability as they are not eco‐friendly, energetically efficient and often involve toxic reducing/capping agents; but phytonanotechnology enabled the synthesis of safe, inexpensive, highly biocompatible NPs. In this regard, thorough understanding of green components and the modulatory effects of different reaction conditions on the physicochemical parameters of green synthesized NPs would be a prerequisite, which is not depicted elsewhere. This review critically analyzes the relevant reaction conditions from their mechanistic viewpoints in plant‐based synthesis of NPs arising fundamental issues which need to be determined carefully. The size, stability and surface chemistry of phytogenic NPs may be fabricated as a function of multiple interconnected reaction parameters and the plant species used. The therapeutic potential of phytogenic NPs may depend on the plant species used; and so the meticulous understanding of physicochemical parameters and the family wise shorting of elite plant species may potentially benefit the theranostic future of plant‐based NPs.

中文翻译：

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植物源性纳米粒子质量改进的生物物理化学参数的关键分析

用于合成纳米粒子 (NPs) 的常规化学方法可能会限制其适用性，因为它们不环保、不节能且通常涉及有毒的还原剂/封端剂；但是植物纳米技术能够合成安全、廉价、高度生物相容的纳米粒子。在这方面，深入了解绿色成分和不同反应条件对绿色合成 NPs 的物理化学参数的调节作用将是一个先决条件，这在其他地方没有描述。这篇综述从其机理的角度批判性地分析了相关反应条件，这些反应条件在基于植物的 NPs 合成中产生了需要仔细确定的基本问题。规模，植物源性纳米粒子的稳定性和表面化学可以根据多个相互关联的反应参数和所使用的植物物种来制造。植物源性 NP 的治疗潜力可能取决于所使用的植物种类；因此，对理化参数的细致了解和优良植物物种的家族化短线可能有利于植物基纳米粒子的治疗学未来。