An investigation of how mitotic spindle size scales with cell size in early zebrafish embryos reveals fundamental principles of spindle organization. Spindle size depends primarily on microtubule number, which is regulated by a reaction–diffusion system when cells are large, and by signals from the plasma membrane when they are small.

中文翻译：

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细胞生物学：有丝分裂纺锤体的大小缩放。

对早期斑马鱼胚胎中有丝分裂纺锤体大小与细胞大小的比例关系的研究揭示了纺锤体组织的基本原理。纺锤体的大小主要取决于微管的数量，当细胞较大时，微管数量受到反应扩散系统的调节；当细胞较小时，其受质膜信号的调节。