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Soft tissue myoepithelial carcinoma—a case report with molecular and electron microscopic analysis
APMIS ( IF 2.8 ) Pub Date : 2020-12-18 , DOI: 10.1111/apm.13105
Erika Wernheden 1 , Alessandro Venzo 1 , Søren Daugaard 2 , Anand C Loya 2
Affiliation  

Myoepithelial tumors are rare neoplasms that primarily occur in the salivary gland but over the last decade have also been described in other locations, including soft tissue. Myoepithelial carcinoma of soft tissue has shown to have a recurrence rate of 39–42% and distant metastases in 32–53% of patients. The only known predictor of malignancy in soft tissue myoepithelial tumors described is cytologic atypia. There are no other validated criteria for differentiating benign and malignant tumors, neither for grading nor for standard of care for these tumor types. Herein, we present a case of myoepithelial carcinoma of inguinal soft tissue in a 37‐year male. We also describe the molecular and previously sparingly described detailed electron microscopic features of this case.

中文翻译:

软组织肌上皮癌-通过分子和电子显微镜分析的病例报告

肌上皮肿瘤是罕见的肿瘤,主要发生在唾液腺中,但是在过去的十年中,也已经在包括软组织在内的其他位置进行了描述。已显示软组织肌上皮癌的复发率为39–42%,远处转移的患者为32–53%。所描述的软组织肌上皮肿瘤中恶性肿瘤的唯一已知预测因子是细胞学非典型性。对于区分良性和恶性肿瘤,没有其他验证的标准,既没有针对这些肿瘤类型的分级,也没有针对这些肿瘤类型的护理标准。在此,我们介绍了一例37岁男性腹股沟软组织肌上皮癌的病例。我们还描述了这种情况的分子和先前很少描述的详细电子显微镜特征。
更新日期:2020-12-18
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