Abstract

Background

This study evaluated the prevalence and symptoms of sexual and urinary disorders in patients with multiple sclerosis. Methods: MEDLINE, ISI Web of Science, PubMed, EMBASE, Scopus, ProQuest, and Science Direct were searched to find the articles published during 2000–2018.The quality of the selected studies was determined based on STROBE checklist. Moreover, I ² and Cochrane Q-test were used to determine heterogeneity. Also, fixed effects and/or random effects models were applied to estimate pooled prevalence. The effects of variables were then assessed through subgroup analysis and meta-regression. Results: The pooled prevalence of sexual and urinary disorders was 52.2% (95% CI [44.2–60.1]) and 49.5% (95% CI [25.3–73.8]), respectively. Notably, the pooled prevalence of sexual disorders was found to be 47.1% (95% CI [36.0–58.3]) in women and 48.4% (95% CI [37.8–59.0]) in men. Conclusion: Supportive measures, counseling, and education, should be incorporated into the routine healthcare programs for patients with MS.

中文翻译：

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多发性硬化症患者的泌尿系统疾病和性功能障碍：系统评价和荟萃分析

摘要

背景

这项研究评估了多发性硬化症患者的性和泌尿疾病的患病率和症状。方法：检索MEDLINE，ISI Web of Science，PubMed，EMBASE，Scopus，ProQuest和Science Direct，以查找2000-2018年发表的文章。根据STROBE清单确定所选研究的质量。此外，使用I ²和Cochrane Q检验确定异质性。同样，固定效应和/或随机效应模型被应用于估计合并患病率。然后通过亚组分析和荟萃回归评估变量的影响。结果：性和泌尿系统疾病的合并患病率分别为52.2％（95％CI [44.2-60.1]）和49.5％（95％CI [25.3-73.8]）。值得注意的是，女性混合性疾病的患病率为47.1％（95％CI [36.0-58.3]），男性为48.4％（95％CI [37.8-59.0]）。结论：支持性措施，咨询和教育应纳入MS患者的常规医疗保健计划。