Background: The prognostic significance of follow-up (f/u) renal function for patients undergoing percutaneous coronary intervention (PCI) remains unknown. This study sought to investigate the prognostic implications of f/u renal function in patients undergoing PCI. Methods: A drug-eluting stent registry was used. We divided patients into 4 groups according to the change in the estimated glomerular filtration rate (eGFR) before PCI and 3–6 months after PCI. Patients with normal pre-PCI eGFR and f/u eGFR were assigned to group 1. Those with normal pre-PCI eGFR and abnormal f/u eGFR were assigned to group 2. Patients with abnormal pre-PCI eGFR and normal f/u eGFR were assigned to group 3. Patients with abnormal pre-PCI eGFR and f/u eGFR were allocated into group 4. Results: A total of 4,899 PCI patients were enrolled. The death rate in group 1, 2, 3, and 4 at 3 years was 2, 11, 4, and 9%, respectively. This showed significant differences between groups, except between groups 2 and 4. The prognosis of a group with aggravation from normal renal function was worse than that of a group with recovery from abnormal renal function. A prediction model that combines clinical risk factors and f/u eGFR has more power for predicting clinical outcomes than a combination of clinical risk factors and pre-PCI eGFR. Conclusion: Post-PCI eGFR was more accurate for predicting patient outcomes than pre-PCI eGFR.
Cardiorenal Med

中文翻译：

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经皮冠状动脉介入治疗后 3-6 个月估计肾小球滤过率的预后价值

背景：对于接受经皮冠状动脉介入治疗 (PCI) 的患者，随访 (f/u) 肾功能的预后意义仍然未知。本研究旨在调查接受 PCI 的患者 f/u 肾功能对预后的影响。方法：使用药物洗脱支架登记。我们根据 PCI 前和 PCI 后 3-6 个月估计肾小球滤过率 (eGFR) 的变化将患者分为 4 组。PCI 前 eGFR 和 f/u eGFR 正常的患者被分配到第 1 组。PCI 前 eGFR 正常且 f/u eGFR 异常的患者被分配到第 2 组。PCI 前 eGFR 异常且 f/u eGFR 正常的患者被分配到第 3 组。 PCI 前 eGFR 和 f/u eGFR 异常的患者被分配到第 4 组。结果：共招募了 4,899 名 PCI 患者。3 年时第 1、2、3 和 4 组的死亡率分别为 2%、11%、4% 和 9%。这表明除第2组和第4组外，各组之间存在显着差异。肾功能正常恶化组的预后比肾功能异常恢复组差。结合临床风险因素和 f/u eGFR 的预测模型比结合临床风险因素和 PCI 前 eGFR 更能预测临床结果。结论： PCI 后 eGFR 比 PCI 前 eGFR 在预测患者预后方面更准确。
心肾医学