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Prognostic value of natural killer cell/T cell ratios for disease activity in multiple sclerosis
European Journal of Neurology ( IF 5.1 ) Pub Date : 2020-12-16 , DOI: 10.1111/ene.14680
Max Mimpen 1 , Anne-Hilde Muris 1 , Linda Rolf 1 , Oliver Gerlach 2 , Jens Kuhle 3 , Raymond Hupperts 1, 2 , Joost Smolders 4, 5 , Jan Damoiseaux 6
Affiliation  

Natural killer (NK) cells may play a role in multiple sclerosis (MS). Ratios of NK cells to CD4+ T cells have been proposed as a biomarker for the therapeutic effect of stem cell transplantation in MS. The objectives here were to explore the relevance of this ratio in MS patients by analysing NK and T cell subsets, as well as their prognostic value for disease activity.

中文翻译:

自然杀伤细胞/T 细胞比率对多发性硬化症疾病活动的预后价值

自然杀伤 (NK) 细胞可能在多发性硬化症 (MS) 中发挥作用。NK 细胞与 CD4 + T 细胞的比率已被提议作为 MS 干细胞移植治疗效果的生物标志物。这里的目标是通过分析 NK 和 T 细胞亚群,以及它们对疾病活动的预后价值,来探索该比率在 MS 患者中的相关性。
更新日期:2021-02-08
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