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Thioredoxin deficiency exacerbates vascular dysfunction during diet-induced obesity in small mesenteric artery in mice
Microcirculation ( IF 2.4 ) Pub Date : 2020-12-14 , DOI: 10.1111/micc.12674
Shannon Dunn 1 , Robert H Hilgers 1 , Kumuda C Das 1
Affiliation  

Thioredoxin (Trx) is a small cellular redox protein with established antioxidant and disulfide reductase properties. We hypothesized that Trx deficiency in mice would cause increased oxidative stress with consequent redox imbalance that would exacerbate obesity-induced vascular dysfunction.

中文翻译:

硫氧还蛋白缺乏加剧了小鼠肠系膜小动脉饮食诱导肥胖过程中的血管功能障碍

硫氧还蛋白 (Trx) 是一种小细胞氧化还原蛋白,具有确定的抗氧化和二硫化物还原酶特性。我们假设小鼠的 Trx 缺乏会导致氧化应激增加,从而导致氧化还原失衡,从而加剧肥胖引起的血管功能障碍。
更新日期:2020-12-14
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