The Schiff base ligand was prepared from 4‐aminoantipyrine, acetamide, and m‐phenylenediamine. Metal salts used for the synthesis of these complexes are Co(II), Ni(II), Cu(II), and Zn(II) acetates. The elemental analysis results are in accordance with proposed formula assigned to these complexes. In the IR spectra, the imine band is shifted to a lower wave number in the complexes. UV spectra and magnetic susceptibility measurements proposed square planar geometry for Co(II), Ni(II), and Cu(II) complexes and tetrahedral geometry for Zn(II) complex. The grain size of the metal complexes was estimated by the Scherrer formula using powder XRD. In the present study, the ligand and its metal complexes are found to be nanocrystalline. Thermal decomposition pattern is in agreement with the proposed formula of the complexes. Irreversible redox behavior of the complex was identified by cyclic voltammetric analysis. The photocatalytic activity of the synthesized complexes are high under UV‐spectra using methylene blue dye. DNA studies reveal that the synthesized complexes exhibit both DNA cleavage and DNA binding properties. Antibacterial and antifungal activities were done by the minimum inhibitory concentration (MIC) method. Anticancer activity shows that Cu(II) complex has the highest cytotoxic effect in SK‐MEL‐28 cell line.

中文翻译：

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4-氨基安替比林衍生的席夫碱的Co（II），Ni（II），Cu（II）和Zn（II）配合物。合成，结构阐明，热学，生物学研究和光催化活性

席夫碱配体，由4-氨基安，乙酰胺，而制得米苯二胺。用于合成这些配合物的金属盐是乙酸钴（II），镍（II），铜（II）和锌（II）。元素分析结果与分配给这些配合物的拟议公式相符。在红外光谱中，亚胺谱带在复合物中移动到较低的波数。紫外光谱和磁化率测量提出了Co（II），Ni（II）和Cu（II）配合物的方形平面几何形状以及Zn（II）配合物的四面体几何形状。金属配合物的晶粒尺寸使用粉末XRD通过Scherrer公式估算。在本研究中，发现配体及其金属配合物是纳米晶体。热分解模式与所提出的配合物配方一致。通过循环伏安分析鉴定了该络合物的不可逆氧化还原行为。使用亚甲基蓝染料在紫外光谱下，合成的配合物具有很高的光催化活性。DNA研究表明，合成的复合物同时具有DNA裂解和DNA结合特性。抗菌和抗真菌活性通过最小抑菌浓度（MIC）方法完成。抗癌活性表明，Cu（II）复合物在SK‐MEL‐28细胞系中具有最高的细胞毒性作用。