Cells within the tumor microenvironment can influence tumor progression; however, genetic alterations in stromal cell populations remain largely unexplored. In this issue, Zhou et al. combine multiomics single-cell sequencing and identify prevalent genetic alterations in colorectal cancer stromal cell populations.

中文翻译：

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基质细胞在结直肠癌中表现出普遍的遗传异常

肿瘤微环境中的细胞可以影响肿瘤的进展。然而，基质细胞群体的遗传改变仍未得到充分探索。在本期中，Zhou等。结合多组学单细胞测序技术，鉴定大肠癌基质细胞群中普遍存在的遗传变异。