Expert Review of Anti-infective Therapy ( IF 5.7 ) Pub Date : 2020-12-21 , DOI: 10.1080/14787210.2021.1863789 Mera A Ababneh 1 , Mutaz Jaber 1 , Abeer Rababa'h 1 , Eshraq Alabweny 1
ABSTRACT
Objective
To quantify antimicrobial use in inpatients setting as part of antimicrobial stewardship program surveillance.
Method
Antimicrobial use was obtained using a pre-designed data collection form in this point prevalence study. Setting: The study was conducted in a tertiary academic hospital in the North of Jordan on 13 August 2018. Main outcome measures: antimicrobial use was determined using two methods: defined daily use (DDD) and days of therapy (DOT).
Results
This study identified antimicrobial use in 144 patients. Carbapenems, glycopeptides, and piperacillin-tazobactam were the most utilized antimicrobials in the inpatients’ setting in both measures DDD and DOT. The highest prescription rate of antibiotics was in the internal medicine wards (49.8 DDD/100 admissions), followed by surgery wards (33.2 DDD/100 admissions) and intensive care unit (20.6 DDD/100 admissions).
Conclusion
This surveillance study addressed patterns of antimicrobial usage in inpatients settings in a tertiary care hospital in Jordan. This practice is feasible and could be adopted routinely by antimicrobial stewardship programs.
中文翻译:
三级学术医院的抗菌药物使用流行率:抗菌药物管理计划的场所
摘要
客观的
作为抗菌药物管理计划监测的一部分,量化住院患者的抗菌药物使用情况。
方法
在该点流行率研究中,使用预先设计的数据收集表获得了抗菌剂的使用。设置:该研究于 2018 年 8 月 13 日在约旦北部的一家三级学术医院进行。主要结果测量:使用两种方法确定抗菌素使用情况:确定每日使用量 (DDD) 和治疗天数 (DOT)。
结果
该研究确定了 144 名患者使用抗生素。碳青霉烯类、糖肽类和哌拉西林-他唑巴坦是住院患者环境中 DDD 和 DOT 两项指标中使用最多的抗菌药物。抗生素处方率最高的是内科病房(49.8 DDD/100人次),其次是外科病房(33.2 DDD/100人次)和重症监护病房(20.6 DDD/100人次)。
结论
这项监测研究解决了约旦一家三级医院住院患者使用抗菌素的模式。这种做法是可行的,并且可以被抗菌药物管理计划常规采用。